[1][Aggarwal BB, Shishodia S, Sandur SK, Pandey MK, Sethi G. Inflammation and cancer: how hot is the link?. Biochem Pharmacol. 2006;72(11):1605-1621. doi:10.1016/j.bcp.2006.06.029]
[2][Amor S, Peferoen LA, Vogel DY, et al. Inflammation in neurodegenerative diseases--an update. Immunology. 2014;142(2):151-166. doi:10.1111/imm.12233]
[3][Amor S, Puentes F, Baker D, van der Valk P. Inflammation in neurodegenerative diseases. Immunology. 2010;129(2):154-169. doi:10.1111/j.1365-2567.2009.03225.x]
[4][Aggarwal BB, Harikumar KB. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int J Biochem Cell Biol. 2009;41(1):40-59. doi:10.1016/j.biocel.2008.06.010]
[5][Basnet P, Skalko-Basnet N. Curcumin: an anti-inflammatory molecule from a curry spice on the path to cancer treatment. Molecules. 2011;16(6):4567-4598. Published 2011 Jun 3. doi:10.3390/molecules16064567]
[6][Recio MC, Andujar I, Rios JL. Anti-inflammatory agents from plants: progress and potential. Curr Med Chem. 2012;19(14):2088-2103. doi:10.2174/092986712800229069]
[7][Tyagi P, Khan HA. Amelioration of oxidative stress in the joint tissue may be the basis for the antiarthritic activity of Terminalia arjuna bark extract. Int J Rheum Dis. 2018;21(12):2079-2088. doi:10.1111/1756-185X.12429]
[8][Godin AM, Araújo DP, Menezes RR, et al. Activities of 2-phthalimidethanol and 2-phthalimidethyl nitrate, phthalimide analogs devoid of the glutarimide moiety, in experimental models of inflammatory pain and edema. Pharmacol Biochem Behav. 2014;122:291-298. doi:10.1016/j.pbb.2014.04.008]
[9][Kloesch B, Becker T, Dietersdorfer E, Kiener H, Steiner G. Anti-inflammatory and apoptotic effects of the polyphenol curcumin on human fibroblast-like synoviocytes. Int Immunopharmacol. 2013;15(2):400-405. doi:10.1016/j.intimp.2013.01.003]
[10][Chandran B, Goel A. A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis. Phytother Res. 2012;26(11):1719-1725. doi:10.1002/ptr.4639]
[11][Park C, Moon DO, Choi IW, et al. Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis. Int J Mol Med. 2007;20(3):365-372.]
[12][Moon DO, Kim MO, Choi YH, Park YM, Kim GY. Curcumin attenuates inflammatory response in IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse model. Int Immunopharmacol. 2010;10(5):605-610. doi:10.1016/j.intimp.2010.02.011]
[13][Atreya I, Atreya R, Neurath MF. NF-kappaB in inflammatory bowel disease. J Intern Med. 2008;263(6):591-596. doi:10.1111/j.1365-2796.2008.01953.x]
[14][Topcu-Tarladacalisir Y, Akpolat M, Uz YH, et al. Effects of curcumin on apoptosis and oxidoinflammatory regulation in a rat model of acetic acid-induced colitis: the roles of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase. J Med Food. 2013;16(4):296-305. doi:10.1089/jmf.2012.2550]
[15][Liu L, Shang Y, Li M, Han X, Wang J, Wang J. Curcumin ameliorates asthmatic airway inflammation by activating nuclear factor-E2-related factor 2/haem oxygenase (HO)-1 signalling pathway. Clin Exp Pharmacol Physiol. 2015;42(5):520-529. doi:10.1111/1440-1681.12384]
[16][Bhardwaj P, Yadav RK. Chronic pancreatitis: role of oxidative stress and antioxidants. Free Radic Res. 2013;47(11):941-949. doi:10.3109/10715762.2013.804624]
[17][Gulcubuk A, Haktanir D, Cakiris A, et al. Effects of curcumin on proinflammatory cytokines and tissue injury in the early and late phases of experimental acute pancreatitis. Pancreatology. 2013;13(4):347-354. doi:10.1016/j.pan.2013.05.005]
[18][Nagar AB, Gorelick FS. Acute pancreatitis. Curr Opin Gastroenterol. 2004;20(5):439-443. doi:10.1097/00001574-200409000-00004]
[19][Dhillon N, Aggarwal BB, Newman RA, et al. Phase II trial of curcumin in patients with advanced pancreatic cancer. Clin Cancer Res. 2008;14(14):4491-4499. doi:10.1158/1078-0432.CCR-08-0024]
[20][Santos AM, Lopes T, Oleastro M, et al. Curcumin inhibits gastric inflammation induced by Helicobacter pylori infection in a mouse model. Nutrients. 2015;7(1):306-320. Published 2015 Jan 6. doi:10.3390/nu7010306]
[21][Kurup VP, Barrios CS. Immunomodulatory effects of curcumin in allergy. Mol Nutr Food Res. 2008;52(9):1031-1039. doi:10.1002/mnfr.200700293]
[22][Nilani P, Kasthuribai N, Duraisamy B, et al. Invitro antioxidant activity of selected antiasthmatic herbal constituents. Anc Sci Life. 2009;28(4):3-6.]
[23][Lavoie S, Chen Y, Dalton TP, et al. Curcumin, quercetin, and tBHQ modulate glutathione levels in astrocytes and neurons: importance of the glutamate cysteine ligase modifier subunit. J Neurochem. 2009;108(6):1410-1422. doi:10.1111/j.1471-4159.2009.05908.x]
[24][Karlstetter M, Lippe E, Walczak Y, et al. Curcumin is a potent modulator of microglial gene expression and migration. J Neuroinflammation. 2011;8:125. Published 2011 Sep 29. doi:10.1186/1742-2094-8-125]
[25][Wang J, Zhang YJ, Du S. The protective effect of curcumin on Aβ induced aberrant cell cycle reentry on primary cultured rat cortical neurons. Eur Rev Med Pharmacol Sci. 2012;16(4):445-454.]
[26][Darvesh AS, Carroll RT, Bishayee A, Novotny NA, Geldenhuys WJ, Van der Schyf CJ. Curcumin and neurodegenerative diseases: a perspective. Expert Opin Investig Drugs. 2012;21(8):1123-1140. doi:10.1517/13543784.2012.693479]
[27][Wang J, Zhang YJ, Du S. The protective effect of curcumin on Aβ induced aberrant cell cycle reentry on primary cultured rat cortical neurons. Eur Rev Med Pharmacol Sci. 2012;16(4):445-454.]
[28][Ye J, Zhang Y. Curcumin protects against intracellular amyloid toxicity in rat primary neurons. Int J Clin Exp Med. 2012;5(1):44-49.]
[29][Jiang H, Tian X, Guo Y, Duan W, Bu H, Li C. Activation of nuclear factor erythroid 2-related factor 2 cytoprotective signaling by curcumin protect primary spinal cord astrocytes against oxidative toxicity. Biol Pharm Bull. 2011;34(8):1194-1197. doi:10.1248/bpb.34.1194]
[30][Cho JW, Lee KS, Kim CW. Curcumin attenuates the expression of IL-1beta, IL-6, and TNF-alpha as well as cyclin E in TNF-alpha-treated HaCaT cells; NF-kappaB and MAPKs as potential upstream targets. Int J Mol Med. 2007;19(3):469-474.]
[31][Cole GM, Teter B, Frautschy SA. Neuroprotective effects of curcumin. Adv Exp Med Biol. 2007;595:197-212. doi:10.1007/978-0-387-46401-5_8]
[32][Ono K, Hasegawa K, Naiki H, Yamada M. Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro. J Neurosci Res. 2004;75(6):742-750. doi:10.1002/jnr.20025]
[33][Garcia-Alloza M, Borrelli LA, Rozkalne A, Hyman BT, Bacskai BJ. Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model. J Neurochem. 2007;102(4):1095-1104. doi:10.1111/j.1471-4159.2007.04613.x]
[34][Tripanichkul W, Jaroensuppaperch EO. Curcumin protects nigrostriatal dopaminergic neurons and reduces glial activation in 6-hydroxydopamine hemiparkinsonian mice model. Int J Neurosci. 2012;122(5):263-270. doi:10.3109/00207454.2011.648760]
[35][Hu M, Du Q, Vancurova I, et al. Proapoptotic effect of curcumin on human neutrophils: activation of the p38 mitogen-activated protein kinase pathway. Crit Care Med. 2005;33(11):2571-2578. doi:10.1097/01.ccm.0000186760.20502.c7]
[36][Literat A, Su F, Norwicki M, et al. Regulation of pro-inflammatory cytokine expression by curcumin in hyaline membrane disease (HMD). Life Sci. 2001;70(3):253-267. doi:10.1016/s0024-3205(01)01398-4]
[37][Thresiamma KC, George J, Kuttan R. Protective effect of curcumin, ellagic acid and bixin on radiation induced toxicity. Indian J Exp Biol. 1996;34(9):845-847.]
[38][Crouch E. Pathobiology of pulmonary fibrosis. Am J Physiol. 1990;259(4 Pt 1):L159-L184. doi:10.1152/ajplung.1990.259.4.L159]
[39][Punithavathi D, Venkatesan N, Babu M. Curcumin inhibition of bleomycin-induced pulmonary fibrosis in rats. Br J Pharmacol. 2000;131(2):169-172. doi:10.1038/sj.bjp.0703578]
[40][Punithavathi D, Venkatesan N, Babu M. Protective effects of curcumin against amiodarone-induced pulmonary fibrosis in rats. Br J Pharmacol. 2003;139(7):1342-1350. doi:10.1038/sj.bjp.0705362]
[41][Venkatesan N, Chandrakasan G. Modulation of cyclophosphamide-induced early lung injury by curcumin, an anti-inflammatory antioxidant. Mol Cell Biochem. 1995;142(1):79-87. doi:10.1007/BF00928916][Venkatesan N. Pulmonary protective effects of curcumin against paraquat toxicity. Life Sci. 2000;66(2):PL21-PL28. doi:10.1016/s0024-3205(99)00576-7]
[42][Venkatesan N. Pulmonary protective effects of curcumin against paraquat toxicity. Life Sci. 2000;66(2):PL21-PL28. doi:10.1016/s0024-3205(99)00576-7]
[43][Broaddus, V. C., Ernst, J. D., King Jr, T. E., Lazarus, S. C., Sarmiento, K. F., Schnapp, L. M., ... & Gotway, M. B. (Eds.). (2021). Murray & Nadel's Textbook of Respiratory Medicine E-Book. Elsevier Health Sciences.]
[44][Roth M, Black JL. Transcription factors in asthma: are transcription factors a new target for asthma therapy?. Curr Drug Targets. 2006;7(5):589-595. doi:10.2174/138945006776818638]
[45][Oh SW, Cha JY, Jung JE, et al. Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-κB inhibition. J Ethnopharmacol. 2011;136(3):414-421. doi:10.1016/j.jep.2010.07.026]
[46][Walsh GM, Al-Rabia M, Blaylock MG, Sexton DW, Duncan CJ, Lawrie A. Control of eosinophil toxicity in the lung. Curr Drug Targets Inflamm Allergy. 2005;4(4):481-486. doi:10.2174/1568010054526296]
[47][Leckie MJ. Anti-interleukin-5 monoclonal antibodies: preclinical and clinical evidence in asthma models. Am J Respir Med. 2003;2(3):245-259. doi:10.1007/BF03256653]
[48][Pease JE. Asthma, allergy and chemokines. Curr Drug Targets. 2006;7(1):3-12. doi:10.2174/138945006775270204]
[49][Berg AH, Scherer PE. Adipose tissue, inflammation, and cardiovascular disease. Circ Res. 2005;96(9):939-949. doi:10.1161/01.RES.0000163635.62927.34]
[50][Lastra G, Manrique C. Perivascular adipose tissue, inflammation and insulin resistance: link to vascular dysfunction and cardiovascular disease. Horm Mol Biol Clin Investig. 2015;22(1):19-26. doi:10.1515/hmbci-2015-0010]
[51][Jain SK, Rains J, Croad J, Larson B, Jones K. Curcumin supplementation lowers TNF-alpha, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNF-alpha, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats. Antioxid Redox Signal. 2009;11(2):241-249. doi:10.1089/ars.2008.2140]
[52][Aggarwal BB. Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals. Annu Rev Nutr. 2010;30:173-199. doi:10.1146/annurev.nutr.012809.104755]
[53][Talpur N, Echard B, Ingram C, Bagchi D, Preuss H. Effects of a novel formulation of essential oils on glucose-insulin metabolism in diabetic and hypertensive rats: a pilot study. Diabetes Obes Metab. 2005;7(2):193-199. doi:10.1111/j.1463-1326.2004.00386.x]
[54][Shin SK, Ha TY, McGregor RA, Choi MS. Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism. Mol Nutr Food Res. 2011;55(12):1829-1840. doi:10.1002/mnfr.201100440]
[55][Kaur G, C M. Amelioration of obesity, glucose intolerance, and oxidative stress in high-fat diet and low-dose streptozotocin-induced diabetic rats by combination consisting of "curcumin with piperine and quercetin". ISRN Pharmacol. 2012;2012:957283. doi:10.5402/2012/957283]
[56][Seo KI, Choi MS, Jung UJ, et al. Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabetic db/db mice. Mol Nutr Food Res. 2008;52(9):995-1004. doi:10.1002/mnfr.200700184]
[57][Shimabukuro M, Zhou YT, Levi M, Unger RH. Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes. Proc Natl Acad Sci U S A. 1998;95(5):2498-2502. doi:10.1073/pnas.95.5.2498]
[58][Ejaz A, Wu D, Kwan P, Meydani M. Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice. J Nutr. 2009;139(5):919-925. doi:10.3945/jn.108.100966]
[59][Shao W, Yu Z, Chiang Y, et al. Curcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytes. PLoS One. 2012;7(1):e28784. doi:10.1371/journal.pone.0028784]
[60][Weisberg SP, Leibel R, Tortoriello DV. Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity. Endocrinology. 2008;149(7):3549-3558. doi:10.1210/en.2008-0262]
[61][Jang EM, Choi MS, Jung UJ, et al. Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat-fed hamsters. Metabolism. 2008;57(11):1576-1583. doi:10.1016/j.metabol.2008.06.014]
[62][Yang YS, Su YF, Yang HW, Lee YH, Chou JI, Ueng KC. Lipid-lowering effects of curcumin in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled trial. Phytother Res. 2014;28(12):1770-1777. doi:10.1002/ptr.5197]
[63][Di Pierro F, Bressan A, Ranaldi D, Rapacioli G, Giacomelli L, Bertuccioli A. Potential role of bioavailable curcumin in weight loss and omental adipose tissue decrease: preliminary data of a randomized, controlled trial in overweight people with metabolic syndrome. Preliminary study. Eur Rev Med Pharmacol Sci. 2015;19(21):4195-4202.]